Abstract Session: Neoplasia Saturday, April 30, 5:00 – 6:15 pm Room: Ballroom CD Co-Moderators: Fergal Fleming, MD, Rochester, NY Uma Phatak, MD, Galveston, TX 5:00 pm Introduction 5:05 pm S18 Predicting Neoadjuvant Response in Rectal Cancer: Evaluation of MRI-Radiomic and Clinical Models K.J. Peterson*1, M.T. Simpson1, M.K. Drezdzon1, A. Szabo1, R.A. Ausman1, A.S. Nencka1, C.Y. Peterson1, K.A. Ludwig1, T.J. Ridolfi1; 1Milwaukee, WI 5:11 pm Discussion 5:13 pm S19 Short-Course Radiotherapy Followed by Consolidation Chemotherapy is Safe and Effective in Locally Advanced Rectal Cancer: Comparative Preliminary Results of a Multicenter Cohort Study C. Benlice*1, M.A. Koc1 2 3, B. Gulcu1 2 3, I.A. Bilgin1 2 3, C. Akyol1 2 3, B. Baca1 2 3, E. Ozturk1 2 3, A. Kuzu1 2 3; 1Ankara, Ankara, Turkey, 2Bursa, Bursa, Turkey, 3Istanbul, İstanbul, Turkey 5:19 pm Discussion 5:21 pm S20 Incomplete Resection is Twice as High in Mucinous vs Non-Mucinous Rectal Adenocarcinoma S. Naffouje1, M. Read*1, J. Sanchez1, S. Dessureault1, B. Powers1, S. Dineen1, S. Felder1; 1Tampa, FL 5:27 pm Discussion 5:29 pm S21 Commercially Available BCAT1/IKZF1 CtDNA use in Colorectal Cancer: a Single Provider Experience J.R. Williams1, N. Pluta*2; 1Saint Petersburg, FL, 2Tampa, FL 5:35 pm Discussion 5:37 pm S22 Appendiceal Neoplasm Following Laparoscopic Appendectomy. Are We Missing the Boat? R. Fazl Alizadeh*1, B. Sullivan1, M. Manasa1, P. Ruhi-Williams1, J. Nahmias1, J.C. Carmichael1, N.T. Nguyen1, M.J. Stamos1; 1Irvine, CA 5:43 pm Discussion 5:45 pm S23 Assessment of Patient-Reported Outcomes in Patients With Anal Squamous Cell Cancer Undergoing Combined Modality Therapy J. Taylor*1, J.J. Smith1, A.L. Tin1, I.H. Wei1, M.R. Weiser1, G.M. Nash1, M. Widmar1, A.J. Vickers1, P.B. Paty1, J. Garcia-Aguilar1, E. Pappou1; 1New York, NY 5:51 pm Discussion 5:53 pm S24 Duration of CD4/CD8 Ratio Below 0.5 is Associated With Progression to Anal Cancer in Patients With HIV and High-Grade Disease A. Karim*1, M. Freeman1, Q. Yang1, L. Cherney-Stafford1, R. Striker1, C.B. Sanger1; 1Madison, WI 5:59 pm Discussion 6:01 pm S25 The Use of Protease Inhibitors to Treat Anal Cancer Spheroids Derived From HPV Transgenic Mice H. Johnson*1, T. Moyer1, L. Gunder1, S. Park1, N. Sherer1, E. Carchman1; 1Madison, WI 6:07 pm Discussion 6:09 pm Question and Answer 6:15 pm Adjourn